isis bloggers, take a bit of your day to say Hi to Carli Banks. She has a nice new teaser video for you.
~Ray



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ISIS Pharmaceuticals Inc. (NASDAQ:ISIS) is trading up pre-market on new that it entered a broad collaboration with Ortho-McNeil a Johnson & Johnson (NYSE:JNJ) unit for discovery development and commercialization of antisense drugs to treat metabolic diseases. The company has two drugs here for this but the company bought its entire franchise back and this collaboration will include write 2 diabetes. ISIS will grant to Ortho-McNeil worldwide development and commercialization rights to two of its diabetes development candidates. ISIS 325568 and ISIS 377131 which inhibit the production of glucagon receptor and glucocorticoid receptor. Ortho-McNeil ordain give funding to ISIS to support the fit discovery of novel drugs to treat diabetes and obesity. J&J will continue development of these drugs after the initial collaboration phase. ISIS will receive a $45 million upfront licensing fee and research and development funding over the period of the collaboration. In addition to the licensing fee. ISIS could receive more than $230 million in milestone payments upon successful development and regulatory approvals of ISIS 325568 and ISIS 377131 plus royalties on sales. ISIS may also receive milestones and royalties on the successful development and regulatory approvals of additional drugs discovered as move of the collaboration. Before this morning's news. ISIS had a $1.06 Billion market cap and shares closed yesterday at $12.76. Shares are up 8% at $13.80 after the CEO came on CNBC and its 52-week trading range for its stock was $7.49 to $14.00. On the June 30 balance sheet the company had over $200 million in cash and short-term investments and its be liabilities were listed as $215.97 million. Jon Ogg can be reached at jonogg@247wallst com; he produces the 24/7 protect St. Special Situation Investing Newsletter and he does not own securities in the companies he covers.

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CARLSBAD. Calif. (AP) - Isis Pharmaceuticals Inc said Thursday it is collaborating with Ortho-McNeil a unit of Johnson & Johnson to create treatments for metabolic disorders including Type 2 diabetes. Ortho-McNeil will pay Isis $45 million upfront in a licensing fee and will give research and development funding. Isis said it could receive more than $230 million in milestone payments for development and approvals and royalties on sales. Isis also said it plans to buy in Symphony GenIsis Inc and reacquire the intellectual for several programs. Shares of Isis rose $1.99 or 15.6 percent to $14.75 in premarket trading. The closed at $12.76 Wednesday. procure 2007 Associated Press. All rights reserved. This material may not be published air rewritten or redistributed. You must log in to find this area of the site. If you are not a registered user to sign up for instant find! *ABCMoney co uk does not guarantee the accuracy of any share prices or have quotations displayed. These are not real time quotes; all are delayed by at least twenty minutes and are for information purposes only.

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CARLSBAD. Calif. (AP) - Isis Pharmaceuticals Inc said Thursday it is collaborating with Ortho-McNeil a unit of Johnson & Johnson to develop treatments for metabolic disorders including Type 2 diabetes. Ortho-McNeil will pay Isis $45 million upfront in a licensing fee and ordain provide research and development funding. Isis said it could acquire more than $230 million in milestone payments for development and approvals and royalties on sales. Isis also said it plans to buy in Symphony GenIsis Inc and reacquire the intellectual for several programs. Shares of Isis rose $1.99 or 15.6 percent to $14.75 in premarket trading. The closed at $12.76 Wednesday. Copyright 2007 Associated Press. All rights reserved. This material may not be published air rewritten or redistributed. You must log in to find this area of the site. If you are not a registered user to write up for instant access! *ABCMoney co uk does not pledge the accuracy of any share prices or stock quotations displayed. These are not real time quotes; all are delayed by at least twenty minutes and are for information purposes only.

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CARLSBAD. Calif. (AP) - Isis Pharmaceuticals Inc said Thursday it is collaborating with Ortho-McNeil a unit of Johnson & Johnson to develop treatments for metabolic disorders including Type 2 diabetes. Ortho-McNeil ordain pay Isis $45 million upfront in a licensing fee and will give research and development funding. Isis said it could acquire more than $230 million in milestone payments for development and approvals and royalties on sales. Isis also said it plans to buy in Symphony GenIsis Inc and reacquire the intellectual for several programs. Shares of Isis rose $1.99 or 15.6 percent to $14.75 in premarket trading. The closed at $12.76 Wednesday. Copyright 2007 Associated Press. All rights reserved. This material may not be published air rewritten or redistributed. You must log in to access this area of the place. If you are not a registered user to sign up for instant find! *ABCMoney co uk does not pledge the accuracy of any overlap prices or stock quotations displayed. These are not real time quotes; all are delayed by at least twenty minutes and are for information purposes only.

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CARLSBAD. Calif. (AP) - Isis Pharmaceuticals Inc said Thursday it is collaborating with Ortho-McNeil a unit of Johnson & Johnson to develop treatments for metabolic disorders including write 2 diabetes. Ortho-McNeil ordain pay Isis $45 million upfront in a licensing fee and ordain provide research and development funding. Isis said it could receive more than $230 million in milestone payments for development and approvals and royalties on sales. Isis also said it plans to buy in Symphony GenIsis Inc and reacquire the intellectual for several programs. Shares of Isis rose $1.99 or 15.6 percent to $14.75 in premarket trading. The closed at $12.76 Wednesday. Copyright 2007 Associated touch. All rights reserved. This material may not be published air rewritten or redistributed. You must log in to find this area of the place. If you are not a registered user to sign up for instant find! *ABCMoney co uk does not pledge the accuracy of any overlap prices or stock quotations displayed. These are not real measure quotes; all are delayed by at least twenty minutes and are for information purposes only.

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